2. Hasim Rahman KO 5 Lennox Lewis. April 2001, Gauteng, South Africa.
Rahman was a whopping 25-1 underdog on some books, and Lewis, who was unbeaten since his subsequently avenged loss to Oliver McCall almost seven years earlier (itself quite an upset), was seemingly at his peak. Far more dangerous punchers than Rahman had been taken care of by Lewis, and most saw this bout as a showcase for Lennox; who was all set to meet Nelson Mandela after his expected win. Instead, taking advantage of an ill prepared defending champion, Rahman put on the best performance of his career.
Fury will of course be hoping to achieve far more than Rahman, who turned out to be a one hit wonder; losing by KO to Lewis in the immediate rematch.